Certificate Of Analysis (COA)

What Is a COA?

A Certificate of Analysis (COA) is an official document issued by a laboratory verifying that a product has been tested and complies with defined quality criteria. Within peptide and biotechnology research, COAs deliver essential information regarding purity, composition, and analytical verification, ensuring dependable use in scientific applications.

How Do I Read A COA?

To assess a COA's properly:

  1. Confirm independent testing – The lab should be separate from the supplier and ideally ISO-accredited.
  2. Match product details – Ensure the peptide name, batch/lot number, and other identifiers align with your vial.
  3. Check purity (HPLC) – Purity is the key metric; ≥98% is generally acceptable, while lower values may indicate issues.
  4. Verify molecular weight (MS) – The measured weight should closely match the theoretical value (within ±1–2 Da).
  5. Review moisture & solvents – Water content should be low (ideally <8%), and residual solvents must meet safety limits.
  6. Look for sterility/endotoxin data – Especially critical for injectables; absence of these tests is a red flag.
  7. Check dates – Results should be recent and within the product’s shelf life.

Note: A reliable COA  matches products exactly, shows high purity, correct molecular weight, safe contaminant levels, proper sterility data (if applicable), and up-to-date testing.

 
 
VERIFY

TO REQUEST A COA